منابع مشابه
Effect of 5Fluorouracil on RNA Metabolism in Novikoff Hepatoma Cell&
The resistance of a Novikoff hepatoma cell line (Ni -Si I FdUrd) to 5-fluorouracil (FUra) was reversed by the inclusion of inosine in the culture medium. As the concentration of inosine in the medium was increased, there was a marked increasein the uptakeof [14C]FUra nd conversionto nucleo tides with a corresponding increase in the incorporation into RNA. While FUra alone had no effect on this ...
متن کاملOxaliplatin, 5Fluorouracil and Leucovorin (FOLFOX4) as First Line Chemotherapy in Elderly Patients with Advanced Gastric Cancer.
BACKGROUND Gastric cancer is considered the fourth most common cancer and second most common cause of cancerrelated mortalities worldwide. Gastric cancer develops more frequently among elderly. The oxaliplatin/5FU/leucovorin (FOLFOX) regimen has shown a notable activity against gastric cancer. AIM To evaluate the responses and complications of FOLFOX4 regimen as first line chemotherapy in eld...
متن کاملMANIFESTATIONS OF TOXICITY Organ Toxicity
The discipline of toxicology considers the adverse effects of chemicals, including drugs, and other agents, such as biological toxins and radiation, on biological systems. Toxicity associated with drug action can generally be characterized as either an extension of the therapeutic effect, such as the fatal central nervous system (CNS) depression that may follow a barbiturate overdose, or as an ...
متن کاملنتایج دراز مدت استفاده از 5Fluorouracil در حین عمل جراحی گلوکوم
This prospective study evaluated the long-term results of intraoperative 5-FU in glaucoma patients undergoing trabeculectomy. 14 patients categorized as high risk (10 patients) or medium risk (4 patients) underwent trabeculectomy with 5-FU and were followed for a mean period of 32 months. Patients were evaluated for visual acuity, cup-disc ratio and IOP. The number of medications was also taken...
متن کاملMercury toxicity
Mercury is a metal found in elemental, organic, and inorganic forms in the nature. This substance is present in the composition of earth crust, soil, air, and even in some tissues of plants and sea animals. Each year nearly 3400 tons of mercury compounds are released in the environment, which 95% settle in the soil, 3% in the oceans, and 2% in the atmosphere. Different industrial products li...
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ژورنال
عنوان ژورنال: Cancer
سال: 1999
ISSN: 0008-543X,1097-0142
DOI: 10.1002/(sici)1097-0142(19991001)86:7<1099::aid-cncr1>3.3.co;2-o